Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers. [electronic resource]
Producer: 20121001Description: 5368-77 p. digitalISSN:- 1362-4962
- Animals
- Azacitidine -- analogs & derivatives
- Cells, Cultured
- DNA Methylation
- Decitabine
- Embryonic Stem Cells -- metabolism
- Enzyme Inhibitors -- pharmacology
- Epigenesis, Genetic
- HEK293 Cells
- Humans
- Mice
- Neural Stem Cells -- drug effects
- Octamer Transcription Factor-3 -- genetics
- Plasmids -- genetics
- Promoter Regions, Genetic
- Trans-Activators -- chemistry
- Transcriptional Activation
- Valproic Acid -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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