A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma. [electronic resource]
Producer: 20120827Description: e31046 p. digitalISSN:- 1932-6203
- Adult
- Aged
- Antibodies, Monoclonal, Humanized -- pharmacology
- Brain Neoplasms -- metabolism
- CD4-Positive T-Lymphocytes -- cytology
- CD8-Positive T-Lymphocytes -- cytology
- Daclizumab
- Female
- Glioblastoma -- metabolism
- Humans
- Immune System
- Immunoglobulin G -- pharmacology
- Immunosuppressive Agents -- pharmacology
- Interleukin-2 Receptor alpha Subunit -- antagonists & inhibitors
- Lymphopenia -- metabolism
- Male
- Middle Aged
- Pilot Projects
- T-Lymphocytes -- cytology
- T-Lymphocytes, Regulatory -- metabolism
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
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