Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication. [electronic resource]
Producer: 20120717Description: 14289-300 p. digitalISSN:- 1083-351X
- Chemistry, Pharmaceutical -- methods
- Chromatin -- metabolism
- Crystallography, X-Ray -- methods
- DNA Replication -- physiology
- Drug Design
- Flow Cytometry -- methods
- Genes, Reporter
- HeLa Cells
- Humans
- Inhibitory Concentration 50
- Ligands
- Microscopy, Fluorescence -- methods
- Molecular Conformation
- Peptides -- chemistry
- Phosphorylation
- Proliferating Cell Nuclear Antigen -- metabolism
- Protein Interaction Mapping -- methods
- Recombinant Proteins -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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