A novel 3,4-dihydropyrimidin-2(1H)-one: HIV-1 replication inhibitors with improved metabolic stability. [electronic resource]
Producer: 20120710Description: 2522-6 p. digitalISSN:- 1464-3405
- Animals
- Cell Line, Tumor
- Drug Stability
- HIV Reverse Transcriptase -- antagonists & inhibitors
- HIV-1 -- drug effects
- Humans
- Microsomes, Liver -- metabolism
- Models, Molecular
- Nevirapine -- pharmacology
- Pyrimidinones -- chemical synthesis
- Rats
- Reverse Transcriptase Inhibitors -- chemical synthesis
- Structure-Activity Relationship
- Thiazoles -- chemistry
- Virus Replication -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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