Multifunctional adaptive NS1 mutations are selected upon human influenza virus evolution in the mouse. [electronic resource]
Producer: 20120629Description: e31839 p. digitalISSN:- 1932-6203
- Adaptation, Biological -- drug effects
- Animals
- Biological Assay
- Gene Expression Regulation, Viral -- drug effects
- Half-Life
- Host Specificity -- drug effects
- Humans
- Influenza A virus -- drug effects
- Influenza, Human -- virology
- Interferon-beta -- biosynthesis
- Lung -- drug effects
- Mice
- Molecular Sequence Data
- Mutant Proteins -- metabolism
- Mutation -- genetics
- Orthomyxoviridae Infections -- pathology
- Protein Binding -- drug effects
- Protein Biosynthesis -- drug effects
- RNA, Messenger -- genetics
- Recombination, Genetic -- genetics
- Selection, Genetic
- Viral Nonstructural Proteins -- genetics
- Virulence -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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