PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis. [electronic resource]
Producer: 20120803Description: E1063-9 p. digitalISSN:- 1522-1555
- Amino Acid Substitution
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors -- metabolism
- Cell Line
- Glucose -- physiology
- Hepatocytes -- metabolism
- Humans
- Lipase -- metabolism
- Lipogenesis -- physiology
- Membrane Proteins -- metabolism
- Mutation
- Statistics, Nonparametric
- Transcription, Genetic -- physiology
- Triglycerides -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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