Reduction of metastasis, cell invasion, and adhesion in mouse osteosarcoma by YM529/ONO-5920-induced blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathway. [electronic resource]
Producer: 20120426Description: 402-10 p. digitalISSN:- 1096-0333
- Animals
- Cell Adhesion -- drug effects
- Cell Line, Tumor
- Cell Movement -- drug effects
- Diphosphonates -- pharmacology
- Extracellular Signal-Regulated MAP Kinases -- antagonists & inhibitors
- Gene Expression Regulation, Neoplastic -- drug effects
- Imidazoles -- pharmacology
- Male
- Matrix Metalloproteinases -- genetics
- Mice
- Mice, Inbred C3H
- Mitogen-Activated Protein Kinase Kinases -- antagonists & inhibitors
- Neoplasm Invasiveness -- prevention & control
- Neoplasm Metastasis -- prevention & control
- Osteosarcoma -- drug therapy
- Phosphoinositide-3 Kinase Inhibitors
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- RNA, Messenger -- metabolism
- ras Proteins -- antagonists & inhibitors
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Publication Type: Journal Article
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