Inhibition of mammalian target of rapamycin signaling by CCI-779 (temsirolimus) induces growth inhibition and cell cycle arrest in Cashmere goat fetal fibroblasts (Capra hircus). [electronic resource]
Producer: 20120913Description: 1095-9 p. digitalISSN:- 1557-7430
- Animals
- Cell Cycle Checkpoints -- drug effects
- Enzyme Activation -- drug effects
- Fetus
- Fibroblasts -- cytology
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Goats
- Protein Kinase Inhibitors -- pharmacology
- Ribosomal Protein S6 Kinases, 70-kDa -- metabolism
- S Phase Cell Cycle Checkpoints -- drug effects
- Signal Transduction -- drug effects
- Sirolimus -- analogs & derivatives
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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