Functional characterization of the guanine nucleotide exchange factor (GEF) motif of GIV protein reveals a threshold effect in signaling. [electronic resource]
Producer: 20120330Description: 1961-6 p. digitalISSN:- 1091-6490
- Amino Acid Motifs
- Amino Acid Sequence
- Cell Movement -- drug effects
- GTP-Binding Protein alpha Subunits, Gi-Go -- metabolism
- Guanine Nucleotide Exchange Factors -- chemistry
- HeLa Cells
- Humans
- Insulin -- pharmacology
- Lysophospholipids -- pharmacology
- Microfilament Proteins -- chemistry
- Models, Molecular
- Molecular Sequence Data
- Mutant Proteins -- chemistry
- Mutation -- genetics
- Protein Binding -- drug effects
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- Stress Fibers -- drug effects
- Vesicular Transport Proteins -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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