Presenilin-2 regulates the degradation of RBP-Jk protein through p38 mitogen-activated protein kinase. [electronic resource]
Producer: 20120925Description: 1296-308 p. digitalISSN:- 1477-9137
- Acetylcysteine -- analogs & derivatives
- Ammonium Chloride -- pharmacology
- Cell Line
- Chloroquine -- pharmacology
- Cysteine Proteinase Inhibitors -- pharmacology
- Gene Knockout Techniques
- HEK293 Cells
- Humans
- Immunoglobulin J Recombination Signal Sequence-Binding Protein -- biosynthesis
- Leupeptins -- pharmacology
- Lysosomes -- metabolism
- MAP Kinase Signaling System
- Phosphorylation
- Presenilin-1 -- genetics
- Presenilin-2 -- genetics
- Proteasome Inhibitors
- Proteolysis
- Receptor, Notch1 -- metabolism
- Transcription, Genetic
- Transcriptional Activation
- Ubiquitination
- p38 Mitogen-Activated Protein Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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