Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria. [electronic resource]
Producer: 20120830Description: e36 p. digitalISSN:- 2038-8306
- Anti-Bacterial Agents -- pharmacology
- Autophagy -- drug effects
- Blotting, Western
- Cells, Cultured
- Child
- Chromatin -- metabolism
- Fibroblasts -- drug effects
- Humans
- Lamin Type A
- Nuclear Envelope -- drug effects
- Nuclear Proteins -- metabolism
- Prenylation
- Progeria -- pathology
- Protein Precursors -- metabolism
- Sirolimus -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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