mRNA for N-Bak, a neuron-specific BH3-only splice isoform of Bak, escapes nonsense-mediated decay and is translationally repressed in the neurons. [electronic resource]
Producer: 20120724Description: e269 p. digitalISSN:- 2041-4889
- 5' Flanking Region -- genetics
- Alternative Splicing
- Animals
- Apoptosis -- drug effects
- Codon, Nonsense
- Cycloheximide -- pharmacology
- Embryo, Mammalian
- Exons
- HeLa Cells
- Humans
- Mice
- Mitochondria -- drug effects
- Neurons -- cytology
- Primary Cell Culture
- Protein Biosynthesis -- drug effects
- Protein Isoforms
- Protein Synthesis Inhibitors -- pharmacology
- RNA, Messenger -- biosynthesis
- Transfection
- bcl-2 Homologous Antagonist-Killer Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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