cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function. [electronic resource]
Producer: 20120329Description: 252-9 p. digitalISSN:- 1546-170X
- Animals
- Cyclic GMP-Dependent Protein Kinase Type I
- Cyclic GMP-Dependent Protein Kinases -- physiology
- Cyclic Nucleotide Phosphodiesterases, Type 5 -- drug effects
- Enzyme Activation
- Female
- Hair Cells, Auditory -- metabolism
- Hair Cells, Auditory, Inner -- metabolism
- Hair Cells, Auditory, Outer -- metabolism
- Hearing Loss, Noise-Induced -- genetics
- Imidazoles -- pharmacology
- Mice
- Mice, Mutant Strains
- Noise -- adverse effects
- Phosphodiesterase 5 Inhibitors -- pharmacology
- Piperazines -- pharmacology
- Poly Adenosine Diphosphate Ribose -- biosynthesis
- Poly(ADP-ribose) Polymerases -- metabolism
- Rats
- Rats, Wistar
- Signal Transduction -- genetics
- Sulfones -- pharmacology
- Triazines -- pharmacology
- Up-Regulation -- drug effects
- Vardenafil Dihydrochloride
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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