Prediction of drug clearance in a smoking population: modeling the impact of variable cigarette consumption on the induction of CYP1A2. [electronic resource]
Producer: 20120914Description: 951-60 p. digitalISSN:- 1432-1041
- Adolescent
- Adult
- Caffeine -- pharmacokinetics
- Clozapine -- pharmacokinetics
- Computer Simulation
- Cytochrome P-450 CYP1A2 -- biosynthesis
- Enzyme Induction
- Female
- Humans
- Liver -- metabolism
- Male
- Middle Aged
- Models, Biological
- Serotonin 5-HT2 Receptor Agonists -- pharmacokinetics
- Smoking -- metabolism
- Theophylline -- pharmacokinetics
- Young Adult
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Publication Type: Clinical Trial, Phase I; Journal Article; Meta-Analysis
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