Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in mice. [electronic resource]
Producer: 20120604Description: 59-69 p. digitalISSN:- 1095-9157
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- genetics
- Apoptosis Regulatory Proteins -- genetics
- Bcl-2-Like Protein 11
- CD4-Positive T-Lymphocytes -- metabolism
- Cell Survival -- drug effects
- Cells, Cultured
- Etoposide -- pharmacology
- Female
- Flow Cytometry
- Forkhead Transcription Factors -- genetics
- Gene Expression Profiling
- Green Fluorescent Proteins -- genetics
- Inflammatory Bowel Diseases -- genetics
- Male
- Membrane Proteins -- genetics
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Transgenic
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- genetics
- T-Lymphocytes, Regulatory -- metabolism
- Thymus Gland -- cytology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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