Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody. [electronic resource]
Producer: 20120709Description: 1102-15 p. digitalISSN:- 1097-6825
- Animals
- Anti-Allergic Agents -- pharmacology
- Antibodies, Anti-Idiotypic -- blood
- Antibodies, Monoclonal, Humanized -- blood
- Antibody Affinity -- immunology
- B-Lymphocytes -- drug effects
- Humans
- Immunoglobulin E -- biosynthesis
- Immunoglobulin Fc Fragments -- genetics
- Immunoglobulin G -- biosynthesis
- Immunoglobulin M -- biosynthesis
- Leukocytes, Mononuclear -- metabolism
- Lymphocyte Activation -- immunology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, SCID
- Omalizumab
- Protein Binding -- immunology
- Receptors, Antigen, B-Cell -- antagonists & inhibitors
- Receptors, IgE -- antagonists & inhibitors
- Receptors, IgG -- antagonists & inhibitors
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Publication Type: Journal Article
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