Characterization of suramin binding sites on the human group IIA secreted phospholipase A2 by site-directed mutagenesis and molecular dynamics simulation. [electronic resource]
Producer: 20120416Description: 17-22 p. digitalISSN:- 1096-0384
- Binding Sites
- Fluoresceins -- chemistry
- Group II Phospholipases A2 -- antagonists & inhibitors
- Humans
- Hydrophobic and Hydrophilic Interactions
- Liposomes -- chemistry
- Models, Molecular
- Molecular Dynamics Simulation
- Mutagenesis, Site-Directed
- Protein Binding
- Protein Conformation
- Recombinant Proteins -- antagonists & inhibitors
- Spectrometry, Fluorescence
- Static Electricity
- Structure-Activity Relationship
- Suramin -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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