Targeting sphingosine kinase-1 to inhibit melanoma. [electronic resource]
Producer: 20120829Description: 259-74 p. digitalISSN:- 1755-148X
- Animals
- Apoptosis -- drug effects
- Cell Adhesion -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cyclin D1 -- metabolism
- Down-Regulation -- drug effects
- Fibroblasts -- drug effects
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- Lysophospholipids -- metabolism
- Melanocytes -- drug effects
- Melanoma -- drug therapy
- Mice
- Molecular Targeted Therapy
- Phosphotransferases (Alcohol Group Acceptor) -- antagonists & inhibitors
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- metabolism
- RNA, Small Interfering -- metabolism
- Resting Phase, Cell Cycle -- drug effects
- Skin Neoplasms -- drug therapy
- Sphingosine -- analogs & derivatives
- Staurosporine -- pharmacology
- Thiazoles -- pharmacology
- Up-Regulation -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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