Pharmacological inhibition of caspase and calpain proteases: a novel strategy to enhance the homing responses of cord blood HSPCs during expansion. [electronic resource]
Producer: 20120514Description: e29383 p. digitalISSN:- 1932-6203
- Actins -- chemistry
- Amino Acid Chloromethyl Ketones -- pharmacology
- Animals
- Calpain -- antagonists & inhibitors
- Caspase Inhibitors
- Cell Adhesion -- drug effects
- Cell Adhesion Molecules -- genetics
- Cell Movement -- drug effects
- Cell Polarity -- drug effects
- Cell Size -- drug effects
- Chemokine CXCL12 -- genetics
- Female
- Fetal Blood -- cytology
- Gene Expression Regulation -- drug effects
- Hematopoietic Stem Cells -- cytology
- Humans
- Integrin alpha4 -- metabolism
- Integrin alpha5 -- metabolism
- Mice
- Protease Inhibitors -- pharmacology
- Protein Multimerization -- drug effects
- Protein Structure, Quaternary
- Receptors, CXCR4 -- genetics
- rho GTP-Binding Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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