Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA. [electronic resource]
Producer: 20120514Description: e29291 p. digitalISSN:- 1932-6203
- Adaptor Proteins, Signal Transducing -- metabolism
- Animals
- Cell Line, Tumor
- DEAD Box Protein 58
- DEAD-box RNA Helicases -- metabolism
- Genome, Viral -- immunology
- HIV-1 -- genetics
- Humans
- Immunity, Innate
- Interferon Regulatory Factors -- metabolism
- Leukocytes, Mononuclear -- cytology
- Mice
- Mice, Inbred C57BL
- NF-kappa B -- metabolism
- Nucleic Acid Conformation
- Oligoribonucleotides -- chemistry
- Peroxisomes -- metabolism
- Protein Transport
- RNA, Viral -- chemistry
- Receptors, Immunologic
- Signal Transduction -- immunology
- Viral Proteins -- metabolism
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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