Aspirin-insensitive thromboxane biosynthesis in essential thrombocythemia is explained by accelerated renewal of the drug target. [electronic resource]
Producer: 20120612Description: 3595-603 p. digitalISSN:- 1528-0020
- Acceleration
- Adult
- Aged
- Algorithms
- Anti-Inflammatory Agents, Non-Steroidal -- therapeutic use
- Aspirin -- administration & dosage
- Cross-Over Studies
- Cross-Sectional Studies -- statistics & numerical data
- Cyclooxygenase 1 -- metabolism
- Cyclooxygenase 2 -- metabolism
- Drug Resistance -- drug effects
- Female
- Half-Life
- Humans
- Male
- Metabolic Networks and Pathways -- drug effects
- Middle Aged
- Molecular Targeted Therapy -- methods
- Protein Biosynthesis -- drug effects
- Thrombocythemia, Essential -- drug therapy
- Thromboxane A2 -- biosynthesis
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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