Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence. [electronic resource]
Producer: 20120427Description: 973-983 p. digitalISSN:- 1525-2191
- Animals
- Apoptosis -- drug effects
- Arginine -- analogs & derivatives
- Autophagy -- drug effects
- Azoles -- pharmacology
- Cardiovascular Diseases -- etiology
- Cathepsins -- pharmacology
- Cell Membrane Permeability -- physiology
- Cells, Cultured
- Cellular Senescence -- drug effects
- Collagen Type I -- pharmacology
- Down-Regulation
- Endothelial Cells -- drug effects
- Endothelium, Vascular
- Hydrogen Peroxide -- pharmacology
- Isoindoles
- Lysosomes -- metabolism
- Mice
- Mice, Knockout
- Mice, Transgenic
- Organoselenium Compounds -- pharmacology
- Recombinant Proteins
- Risk Factors
- Sirtuin 1 -- deficiency
- Stem Cells -- drug effects
- Stress, Physiological -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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