Deregulation of the CXCL12/CXCR4 axis in methotrexate chemotherapy-induced damage and recovery of the bone marrow microenvironment. [electronic resource]
Producer: 20120501Description: 104-14 p. digitalISSN:- 1365-2613
- Animals
- Antineoplastic Agents -- adverse effects
- Bone Marrow Cells -- drug effects
- Cell Count
- Cell Lineage
- Cellular Microenvironment -- drug effects
- Chemokine CXCL12 -- genetics
- Colony-Forming Units Assay
- Gene Expression Regulation, Neoplastic -- drug effects
- Matrix Metalloproteinase 9 -- metabolism
- Methotrexate -- adverse effects
- Myeloid Progenitor Cells -- drug effects
- RNA, Messenger -- metabolism
- Rats
- Rats, Sprague-Dawley
- Real-Time Polymerase Chain Reaction
- Receptors, CXCR4 -- genetics
- Recombinant Proteins
- Signal Transduction -- drug effects
- Tissue Inhibitor of Metalloproteinase-1 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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