Wnt3a stimulates Mepe, matrix extracellular phosphoglycoprotein, expression directly by the activation of the canonical Wnt signaling pathway and indirectly through the stimulation of autocrine Bmp-2 expression. [electronic resource]
Producer: 20120419Description: 2287-96 p. digitalISSN:- 1097-4652
- 3T3 Cells
- Animals
- Autocrine Communication
- Base Sequence
- Binding Sites
- Bone Morphogenetic Protein 2 -- genetics
- Calcification, Physiologic
- Carrier Proteins -- metabolism
- Culture Media, Conditioned -- metabolism
- Extracellular Matrix Proteins -- genetics
- Genes, Reporter
- Glycoproteins -- genetics
- Homeodomain Proteins -- genetics
- Intercellular Signaling Peptides and Proteins -- metabolism
- Lymphoid Enhancer-Binding Factor 1 -- metabolism
- Mice
- Molecular Sequence Data
- Myoblasts -- metabolism
- Osteogenesis
- Phosphoproteins -- genetics
- Phosphorylation
- Promoter Regions, Genetic
- RNA Interference
- RNA, Messenger -- metabolism
- Recombinant Proteins -- metabolism
- Smad1 Protein -- metabolism
- Smad5 Protein -- metabolism
- Time Factors
- Transfection
- Up-Regulation
- Wnt Signaling Pathway
- Wnt3A Protein -- metabolism
- beta Catenin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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