Ectopic over-expression of tristetraprolin in human cancer cells promotes biogenesis of let-7 by down-regulation of Lin28. [electronic resource]
Producer: 20120717Description: 3856-69 p. digitalISSN:- 1362-4962
- 3' Untranslated Regions
- Adenocarcinoma -- genetics
- Anaphase-Promoting Complex-Cyclosome
- Cell Growth Processes
- Cell Line, Tumor
- DNA-Binding Proteins -- genetics
- Down-Regulation
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- MicroRNAs -- biosynthesis
- Neoplasms -- genetics
- Ovarian Neoplasms -- genetics
- RNA Stability
- RNA, Messenger -- metabolism
- RNA-Binding Proteins
- Tristetraprolin -- metabolism
- Ubiquitin-Conjugating Enzymes
- Ubiquitin-Protein Ligase Complexes -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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