Lidocaine attenuates cognitive impairment after isoflurane anesthesia in old rats. [electronic resource]
Producer: 20120523Description: 319-27 p. digitalISSN:- 1872-7549
- Aging -- drug effects
- Amyloid beta-Peptides -- metabolism
- Anesthetics, Inhalation -- adverse effects
- Anesthetics, Local -- therapeutic use
- Animals
- Brain -- drug effects
- Cognition Disorders -- chemically induced
- Conditioning, Psychological -- drug effects
- Drug Interactions
- Enzyme-Linked Immunosorbent Assay
- Fear -- drug effects
- Gene Expression Regulation -- drug effects
- Interleukin-1beta -- metabolism
- Isoflurane -- adverse effects
- Lidocaine -- therapeutic use
- Male
- Maze Learning -- drug effects
- Memory, Short-Term -- drug effects
- Microscopy, Electron, Transmission
- Peptide Fragments -- metabolism
- Phosphopyruvate Hydratase -- metabolism
- Rats
- Rats, Inbred F344
- Synapses -- metabolism
- Synaptophysin -- metabolism
- Time Factors
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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