The ATP-sensitive K(+) channel ABCC8 S1369A type 2 diabetes risk variant increases MgATPase activity. [electronic resource]
Producer: 20120213Description: 241-9 p. digitalISSN:- 1939-327X
- ATP-Binding Cassette Transporters -- chemistry
- Adenosine Triphosphatases -- metabolism
- Adenosine Triphosphate -- metabolism
- Alanine -- genetics
- Amino Acid Substitution -- physiology
- Cells, Cultured
- Diabetes Mellitus, Type 2 -- genetics
- Enzyme Activation
- Genetic Predisposition to Disease
- Humans
- KATP Channels -- chemistry
- Models, Molecular
- Polymorphism, Single Nucleotide -- physiology
- Potassium Channels, Inwardly Rectifying -- chemistry
- Protein Structure, Tertiary -- genetics
- Receptors, Drug -- chemistry
- Risk Factors
- Serine -- genetics
- Sulfonylurea Receptors
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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