Development of pulmonary arterial hypertension in mice over-expressing S100A4/Mts1 is specific to females. [electronic resource]
Producer: 20120622Description: 159 p. digitalISSN:- 1465-993X
- Analysis of Variance
- Animals
- Blood Pressure -- genetics
- Blotting, Western
- Cell Proliferation
- Cells, Cultured
- Disease Models, Animal
- Estradiol -- metabolism
- Familial Primary Pulmonary Hypertension
- Female
- Genetic Predisposition to Disease
- Hypertension, Pulmonary -- genetics
- Hypertrophy, Right Ventricular -- genetics
- Immunohistochemistry
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred CBA
- Mice, Transgenic
- Muscle, Smooth, Vascular -- metabolism
- Myocytes, Smooth Muscle -- metabolism
- Phenotype
- Pulmonary Artery -- metabolism
- Real-Time Polymerase Chain Reaction
- Receptor for Advanced Glycation End Products
- Receptors, Immunologic -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- S100 Calcium-Binding Protein A4
- S100 Proteins -- genetics
- Sex Factors
- Signal Transduction
- Up-Regulation
- Ventricular Function, Right
- Ventricular Pressure
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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