Drug resistance to paclitaxel is not only associated with ABCB1 mRNA expression but also with drug accumulation in intracellular compartments in human lung cancer cell lines. [electronic resource]
Producer: 20120831Description: 995-1004 p. digitalISSN:- 1791-2423
- ATP Binding Cassette Transporter, Subfamily B
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- biosynthesis
- Acetylation
- Antineoplastic Agents, Phytogenic -- pharmacokinetics
- Binding Sites
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Line, Tumor
- Drug Resistance, Neoplasm
- Humans
- Lung Neoplasms -- drug therapy
- Microscopy, Confocal
- Paclitaxel -- pharmacokinetics
- Point Mutation
- RNA, Messenger -- biosynthesis
- Tubulin -- genetics
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Publication Type: Journal Article
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