Olomoucine II and purvalanol A inhibit ABCG2 transporter in vitro and in situ and synergistically potentiate cytostatic effect of mitoxantrone. [electronic resource]
Producer: 20120530Description: 312-9 p. digitalISSN:- 1096-1186
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters -- antagonists & inhibitors
- Animals
- Antineoplastic Agents -- pharmacology
- Benzimidazoles -- metabolism
- Breast Neoplasms -- drug therapy
- Cell Line
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Cytostatic Agents -- pharmacology
- Drug Resistance, Neoplasm -- drug effects
- Drug Synergism
- Female
- Glyburide -- metabolism
- Humans
- Mitoxantrone -- pharmacology
- Neoplasm Proteins -- antagonists & inhibitors
- Purines -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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