Phase I study of the safety, tolerability and pharmacokinetics of PHA-848125AC, a dual tropomyosin receptor kinase A and cyclin-dependent kinase inhibitor, in patients with advanced solid malignancies. [electronic resource]
Producer: 20130404Description: 2334-43 p. digitalISSN:- 1573-0646
- Adolescent
- Adult
- Aged
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Drug Administration Schedule
- Female
- Humans
- Male
- Maximum Tolerated Dose
- Middle Aged
- Neoplasms -- drug therapy
- Protein Kinase Inhibitors -- administration & dosage
- Pyrazoles -- administration & dosage
- Quinazolines -- administration & dosage
- Receptor, trkA -- antagonists & inhibitors
- Treatment Outcome
- Young Adult
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Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study
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