Learning from estrogen receptor antagonism: structure-based identification of novel antiandrogens effective against multiple clinically relevant androgen receptor mutants. [electronic resource]
Producer: 20120514Description: 300-12 p. digitalISSN:- 1747-0285
- Androgen Receptor Antagonists -- chemistry
- Anilides -- chemistry
- Binding Sites
- Cell Line, Tumor
- Enzyme Activation -- drug effects
- Humans
- I-kappa B Kinase -- metabolism
- Interleukin-6 -- metabolism
- Molecular Dynamics Simulation
- Mutation
- Nitriles -- chemistry
- Nucleosides -- chemistry
- Protein Structure, Tertiary
- Receptors, Androgen -- chemistry
- Tosyl Compounds -- chemistry
- Triazines -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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