A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage. [electronic resource]
Producer: 20120224Description: 134-46 p. digitalISSN:- 1528-1167
- Amides -- chemistry
- Animals
- Anticonvulsants -- administration & dosage
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Female
- Guinea Pigs
- Hippocampus -- drug effects
- Male
- Mice
- Neurons -- drug effects
- Neuroprotective Agents
- Rats
- Rats, Sprague-Dawley
- Seizures -- drug therapy
- Status Epilepticus -- drug therapy
- Time Factors
- Treatment Outcome
- Valproic Acid -- analogs & derivatives
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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