Resveratrol induces Sirt1-dependent apoptosis in 3T3-L1 preadipocytes by activating AMPK and suppressing AKT activity and survivin expression. [electronic resource]
Producer: 20130124Description: 1100-12 p. digitalISSN:- 1873-4847
- 3T3-L1 Cells
- AMP-Activated Protein Kinases -- antagonists & inhibitors
- Adipocytes, White -- drug effects
- Animals
- Antioxidants -- pharmacology
- Apoptosis -- drug effects
- Caspase Inhibitors -- pharmacology
- Caspases -- chemistry
- Chromatin Assembly and Disassembly -- drug effects
- Down-Regulation -- drug effects
- Gene Silencing
- Inhibitor of Apoptosis Proteins -- antagonists & inhibitors
- Membrane Potential, Mitochondrial -- drug effects
- Mice
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- RNA, Small Interfering
- Repressor Proteins -- antagonists & inhibitors
- Resveratrol
- S Phase -- drug effects
- Second Messenger Systems -- drug effects
- Sirtuin 1 -- antagonists & inhibitors
- Stilbenes -- pharmacology
- Survivin
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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