Genetic polymorphism of cytochrome P450 2D6 determines oestrogen receptor activity of the major infertility drug clomiphene via its active metabolites. [electronic resource]
Producer: 20120705Description: 1145-54 p. digitalISSN:- 1460-2083
- Biotransformation
- Clomiphene -- analogs & derivatives
- Cytochrome P-450 CYP2D6 -- genetics
- Estrogen Antagonists -- metabolism
- Female
- Genotype
- Humans
- Microsomes, Liver -- metabolism
- Molecular Structure
- Polymorphism, Genetic
- Receptors, Estrogen -- antagonists & inhibitors
- Recombinant Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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