Matrix metalloproteinase-10 effectively reduces infarct size in experimental stroke by enhancing fibrinolysis via a thrombin-activatable fibrinolysis inhibitor-mediated mechanism. [electronic resource]
Producer: 20120216Description: 2909-19 p. digitalISSN:- 1524-4539
- Animals
- Bleeding Time
- Brain Ischemia -- drug therapy
- Carotid Artery Diseases -- drug therapy
- Cerebral Hemorrhage -- metabolism
- Cerebral Infarction -- drug therapy
- Disease Models, Animal
- Extracellular Matrix -- metabolism
- Female
- Fibrinolysis -- drug effects
- Fibrinolytic Agents -- pharmacology
- Humans
- Intracranial Thrombosis -- drug therapy
- Male
- Matrix Metalloproteinase 10 -- genetics
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Stroke -- drug therapy
- Thrombin -- metabolism
- Tissue Plasminogen Activator -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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