Sensitivity of acute myeloid leukemia Kasumi-1 cells to binase toxic action depends on the expression of KIT and АML1-ETO oncogenes. [electronic resource]
Producer: 20120829Description: 4090-7 p. digitalISSN:- 1551-4005
- Animals
- Apoptosis
- Bacillus -- enzymology
- Benzamides
- Cell Line, Tumor
- Cell Proliferation
- Cell Survival
- Core Binding Factor Alpha 2 Subunit -- genetics
- Drug Screening Assays, Antitumor
- Endoribonucleases -- toxicity
- Gene Expression Regulation, Leukemic
- Gene Knockdown Techniques
- Humans
- Imatinib Mesylate
- Inhibitory Concentration 50
- Lentivirus -- genetics
- Leukemia, Myeloid, Acute -- drug therapy
- Mice
- Oncogene Proteins, Fusion -- genetics
- Piperazines -- pharmacology
- Proto-Oncogene Proteins c-kit -- antagonists & inhibitors
- Pyrimidines -- pharmacology
- RNA, Small Interfering -- genetics
- RUNX1 Translocation Partner 1 Protein
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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