IL-6 and soluble IL-6 receptor stimulate the production of MMPs and their inhibitors via JAK-STAT and ERK-MAPK signalling in human chondrocytes. [electronic resource]
Producer: 20120917Description: 367-76 p. digitalISSN:- 1095-8355
- Cartilage -- cytology
- Chondrocytes -- cytology
- Flavonoids -- pharmacology
- Gene Expression Regulation -- drug effects
- Humans
- Interleukin-6 -- pharmacology
- Janus Kinase 3 -- genetics
- Matrix Metalloproteinases -- biosynthesis
- Mitogen-Activated Protein Kinases -- genetics
- Plasminogen Activator Inhibitor 1 -- genetics
- Primary Cell Culture
- Protein Kinase Inhibitors -- pharmacology
- Quinazolines -- pharmacology
- Receptors, Interleukin-6 -- metabolism
- Signal Transduction -- drug effects
- Solubility
- Tissue Inhibitor of Metalloproteinases -- genetics
- Urokinase-Type Plasminogen Activator -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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