Spinocerebellar ataxia type 7 cerebellar disease requires the coordinated action of mutant ataxin-7 in neurons and glia, and displays non-cell-autonomous bergmann glia degeneration. [electronic resource]
Producer: 20120104Description: 16269-78 p. digitalISSN:- 1529-2401
- Analysis of Variance
- Animals
- Ataxin-7
- Disease Models, Animal
- Gene Expression Regulation -- genetics
- Humans
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Motor Activity -- genetics
- Mutation -- genetics
- Nerve Tissue Proteins -- genetics
- Neuroglia -- pathology
- Neurons -- pathology
- Peptides -- genetics
- Phenotype
- Prions -- genetics
- RNA, Messenger -- metabolism
- Rotarod Performance Test
- Spinocerebellar Ataxias -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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