Pyrazolone-based anaplastic lymphoma kinase (ALK) inhibitors: control of selectivity by a benzyloxy group. [electronic resource]
Producer: 20120312Description: 7261-4 p. digitalISSN:- 1464-3405
- Administration, Oral
- Anaplastic Lymphoma Kinase
- Animals
- Binding Sites
- Cell Line, Tumor
- Computer Simulation
- Enzyme Activation -- drug effects
- Indoles -- chemistry
- Protein Kinase Inhibitors -- chemical synthesis
- Protein Structure, Tertiary
- Pyrazolones -- chemical synthesis
- Rats
- Receptor Protein-Tyrosine Kinases -- antagonists & inhibitors
- Structure-Activity Relationship
- Vascular Endothelial Growth Factor Receptor-2 -- antagonists & inhibitors
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Publication Type: Journal Article
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