Degradation of p21Cip1 through anaphase-promoting complex/cyclosome and its activator Cdc20 (APC/CCdc20) ubiquitin ligase complex-mediated ubiquitylation is inhibited by cyclin-dependent kinase 2 in cardiomyocytes. [electronic resource]
Producer: 20120221Description: 44057-44066 p. digitalISSN:- 1083-351X
- Anaphase-Promoting Complex-Cyclosome
- Animals
- Cdc20 Proteins
- Cell Cycle
- Cell Cycle Proteins -- metabolism
- Cell Differentiation
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Gene Expression Regulation, Enzymologic
- Humans
- Models, Biological
- Myocytes, Cardiac -- cytology
- Protein Structure, Tertiary
- RNA Processing, Post-Transcriptional
- Rats
- Rats, Sprague-Dawley
- Ubiquitin -- chemistry
- Ubiquitin-Protein Ligase Complexes -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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