Curcumin attenuates diabetic nephropathy by inhibiting PKC-α and PKC-β1 activity in streptozotocin-induced type I diabetic rats. [electronic resource]
Producer: 20120312Description: 1655-65 p. digitalISSN:- 1613-4133
- Animals
- Antioxidants -- therapeutic use
- Curcumin -- therapeutic use
- Diabetes Mellitus, Type 1 -- complications
- Diabetic Nephropathies -- metabolism
- Extracellular Matrix Proteins -- genetics
- Gene Expression Regulation -- drug effects
- Isoenzymes -- antagonists & inhibitors
- Kidney -- drug effects
- MAP Kinase Signaling System -- drug effects
- Male
- NADPH Oxidase 4
- NADPH Oxidases -- metabolism
- Oxidative Stress -- drug effects
- Phosphoproteins -- metabolism
- Protein Kinase C -- antagonists & inhibitors
- Protein Kinase C beta
- Protein Kinase C-alpha -- antagonists & inhibitors
- Protein Kinase Inhibitors -- therapeutic use
- RNA, Messenger -- metabolism
- Random Allocation
- Rats
- Rats, Sprague-Dawley
- Streptozocin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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