Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer. [electronic resource]
Producer: 20120319Description: 1654-62 p. digitalISSN:- 1532-1827
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Antimetabolites, Antineoplastic -- administration & dosage
- Antineoplastic Combined Chemotherapy Protocols -- adverse effects
- Camptothecin -- administration & dosage
- Chemoradiotherapy, Adjuvant -- adverse effects
- Disease-Free Survival
- Fluorouracil -- administration & dosage
- Genotype
- Humans
- Irinotecan
- Methylenetetrahydrofolate Reductase (NADPH2) -- genetics
- Middle Aged
- Pharmacogenetics -- methods
- Polymorphism, Genetic
- Prospective Studies
- Radiation-Sensitizing Agents -- administration & dosage
- Rectal Neoplasms -- enzymology
- Treatment Outcome
- Young Adult
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Publication Type: Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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