Transcriptional changes in OXPHOS complex I deficiency are related to anti-oxidant pathways and could explain the disturbed calcium homeostasis. [electronic resource]
Producer: 20121015Description: 1161-8 p. digitalISSN:- 0006-3002
- Antioxidants -- metabolism
- Calcium -- metabolism
- Cell Cycle Proteins -- metabolism
- Child, Preschool
- DNA Damage
- Electron Transport Complex I -- deficiency
- Endoplasmic Reticulum Stress
- Female
- Fibroblasts -- cytology
- Gene Expression Profiling
- Glutathione -- metabolism
- Homeostasis -- genetics
- Humans
- Infant
- Infant, Newborn
- Male
- Metabolic Networks and Pathways -- genetics
- Mitochondrial Diseases -- genetics
- NF-E2-Related Factor 2 -- metabolism
- Nuclear Proteins -- metabolism
- Oxidative Phosphorylation
- Oxidative Stress
- Selenoproteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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