Drug discovery targeting human 5-HT(2C) receptors: residues S3.36 and Y7.43 impact ligand-binding pocket structure via hydrogen bond formation. [electronic resource]
Producer: 20120328Description: 1-12 p. digitalISSN:- 1879-0712
- Amines -- chemistry
- Drug Delivery Systems
- Drug Design
- Humans
- Hydrogen Bonding
- Ligands
- Mental Disorders -- drug therapy
- Models, Molecular
- Nervous System Diseases -- drug therapy
- Obesity -- drug therapy
- Point Mutation
- Receptor, Serotonin, 5-HT2C -- drug effects
- Serotonin 5-HT2 Receptor Agonists -- pharmacology
- Type C Phospholipases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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