Treatment with imatinib results in reduced IL-4-producing T cells, but increased CD4(+) T cells in the broncho-alveolar lavage of patients with systemic sclerosis. [electronic resource]
Producer: 20120126Description: 293-303 p. digitalISSN:- 1521-7035
- Adult
- Antigens, CD -- analysis
- Benzamides
- Bronchoalveolar Lavage Fluid -- immunology
- CD4-Positive T-Lymphocytes -- drug effects
- Cell Adhesion Molecules -- analysis
- Clinical Trials, Phase II as Topic
- Female
- Humans
- Imatinib Mesylate
- Interleukin-4 -- immunology
- Lung -- diagnostic imaging
- Male
- Middle Aged
- Pilot Projects
- Piperazines -- therapeutic use
- Platelet Endothelial Cell Adhesion Molecule-1 -- analysis
- Protein Kinase Inhibitors -- therapeutic use
- Pyrimidines -- therapeutic use
- Radiography
- Scleroderma, Systemic -- diagnostic imaging
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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