Lipophilicity but not stereospecificity is a major determinant of local anaesthetic-induced cytotoxicity in human T-lymphoma cells. [electronic resource]
Producer: 20120416Description: 35-41 p. digitalISSN:- 1365-2346
- Amides -- toxicity
- Anesthetics, Local -- chemistry
- Apoptosis -- drug effects
- Bupivacaine -- analogs & derivatives
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Flow Cytometry
- Humans
- Inhibitory Concentration 50
- Jurkat Cells
- Lymphoma, T-Cell -- pathology
- Microscopy, Fluorescence
- Necrosis
- Ropivacaine
- Stereoisomerism
- Structure-Activity Relationship
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Publication Type: Journal Article
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