Inhibition of NOTCH3 signalling significantly enhances sensitivity to cisplatin in EBV-associated nasopharyngeal carcinoma. [electronic resource]
Producer: 20120228Description: 471-81 p. digitalISSN:- 1096-9896
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- physiology
- Carcinoma
- Cell Line, Tumor
- Cell Proliferation
- Cell Transformation, Neoplastic -- drug effects
- Cisplatin -- pharmacology
- Epstein-Barr Virus Infections -- complications
- Gene Knockdown Techniques
- Genes, Neoplasm -- physiology
- Humans
- Inhibitor of Apoptosis Proteins -- metabolism
- Mice
- Mice, Nude
- Nasopharyngeal Carcinoma
- Nasopharyngeal Neoplasms -- drug therapy
- Neoplasm Transplantation
- RNA, Small Interfering -- metabolism
- Receptor, Notch3
- Receptors, Notch -- antagonists & inhibitors
- Signal Transduction -- physiology
- Spheroids, Cellular -- physiology
- Transfection
- Transplantation, Heterologous
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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