Wnt inhibitor screen reveals iron dependence of β-catenin signaling in cancers. [electronic resource]
Producer: 20120306Description: 7628-39 p. digitalISSN:- 1538-7445
- Acute Disease
- Administration, Oral
- Benzoates -- pharmacology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Ciclopirox
- Colorectal Neoplasms -- genetics
- Deferasirox
- Deferoxamine -- pharmacology
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic -- drug effects
- HEK293 Cells
- Humans
- Hydrazones -- chemistry
- Iron -- metabolism
- Iron Chelating Agents -- pharmacology
- Leukemia, Myeloid -- drug therapy
- Oligonucleotide Array Sequence Analysis
- Promoter Regions, Genetic -- genetics
- Pyridones -- administration & dosage
- Reverse Transcriptase Polymerase Chain Reaction
- Triazoles -- pharmacology
- Wnt Proteins -- antagonists & inhibitors
- Wnt Signaling Pathway -- drug effects
- beta Catenin -- genetics
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Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
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