Accumulation of wildtype and ALS-linked mutated VAPB impairs activity of the proteasome. [electronic resource]
Producer: 20120213Description: e26066 p. digitalISSN:- 1932-6203
- Amyotrophic Lateral Sclerosis -- genetics
- Animals
- COS Cells
- Chlorocebus aethiops
- Endoplasmic Reticulum -- metabolism
- Endoplasmic Reticulum Stress -- genetics
- Gene Expression Regulation -- genetics
- Humans
- Mutant Proteins -- chemistry
- Mutation
- Proteasome Endopeptidase Complex -- metabolism
- Protein Stability
- Protein Transport -- genetics
- Proteolysis
- Ubiquitin -- metabolism
- Ubiquitination -- genetics
- Vesicular Transport Proteins -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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